منابع مشابه
SPOTLIGHT REVIEW Glucose metabolism and cardiac hypertrophy
The most notable change in the metabolic profile of hypertrophied hearts is an increased reliance on glucose with an overall reduced oxidative metabolism, i.e. a reappearance of the foetal metabolic pattern. In animal models, this change is attributed to the down-regulation of the transcriptional cascades promoting gene expression for fatty acid oxidation and mitochondrial oxidative phosphoryla...
متن کاملDetection of Cardiac Hypertrophy by RVM and SVM Algorithms
The meaning of the hypertropy word is the increasing size.Heart hypertropy is symptoms of increase the thickness of the heart muscle that the left ventricular hypertrophy of them is the most common.The causes of hypertrophy heart disease are high blood pressure , aortic valve stenosis and sport activities respectively. Assessment of that by using ECG signal analysis is essential Because the ris...
متن کاملIncreased glycolytic metabolism in cardiac hypertrophy and congestive failure.
BISHOP, SANFORD P., AND RUTH A. ,~LTSCHULD. hcreased gi’ycdytic metubolism in cardiac hypertrophy and congestive fniluw. Am. J. Physiol. 218(I): 153-159. 1970.-Lactate dehydrogenase isozymes and potential for glycolytic metabolism in vitro were studied in right and left ventricles of 11 dogs with experimental right ventricular hypertrophy (RVH) and congestive heart failure (CHF), 8 dogs with ac...
متن کاملRegulation of glucose metabolism in cardiac muscle.
Introduction In the heart, like in many other tissues, glucose uptake and metabolism is regulated by the availability of substrates including oxygen, by the energy demand and by the hormonal and dietary status of the organism. It is reasonable to assume that heart glycolysis is controlled at several steps, including glucose transport and phosphorylation, and the reaction catalysed by 6-phosphof...
متن کاملCardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization
Pathological cardiac hypertrophy is characterized by a shift in metabolic substrate utilization from fatty acids to glucose, but the molecular events underlying the metabolic remodeling remain poorly understood. Here, we investigated the role of liver X receptors (LXRs), which are key regulators of glucose and lipid metabolism, in cardiac hypertrophic pathogenesis. Using a transgenic approach i...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2011
ISSN: 0008-6363
DOI: 10.1093/cvr/cvr071